A Mathematical Study of a TB Model with Treatment Interruptions and Two Latent Periods
نویسندگان
چکیده
A TB transmission model which incorporates treatment interruptions and two latent periods is presented. The threshold parameter known as the control reproduction number and the equilibria for the model are determined, and the global asymptotical stabilities of the equilibria are studied by constructing the proper Lyapunov functions. The reproduction numbers and numerical simulations show that treatment of active TB cases always helps to control the TB epidemic, while treatment interruptions may have a negative, positive, or no effect on combating TB epidemic.
منابع مشابه
Management of Latent Tuberculosis in Iran
Although screening, finding and treatment of active cases of tuberculosis is very important for control of disease in the community, for reaching to the goals planed by world health organization and approaching to elimination of the disease, it is necessary to find and treat persons with latent infection. Concerning to high prevalence of latent TB in developing countries and resource limitation...
متن کاملعفونت سل نهفته در کارکنان مراکز درمانی: مقاله مروری
The members of Mycobacterium tuberculosis complex (MTBC) known as causative agents of human tuberculosis. Tuberculosis infection is one of the most important occupational risks for healthcare workers (HCWs) in most countries, such as Iran. In general, there are two types of tuberculosis, they include: latent infection and active TB. Latent tuberculosis infection (LTBI) means: a patient is infec...
متن کاملQuantiFERON-TB Gold and Tuberculin Skin Test for the Diagnosis of Latent Tuberculosis Infection in Children
Background: Appropriate diagnosis and treatment of latent tuberculosis infection (LTBI) play the most important role in the control of tuberculosis. This study aimed to determine the prevalence of LTBI among healthy tuberculosis unexposed children vaccinated with BCG using the tuberculin skin test (TST) and QuantiFERON TB Gold In-Tube (QFT-GIT) and comparing the agreement between the two tests....
متن کاملGlobal properties of a tuberculosis model with lost sight and multi-compartment of latents
A tuberculosis (TB) model with lost sight and multiple latent classes is considered and studied. We derive the basic reproduction ratio $mathcal R_0$. There is always a globally asymptotically stable equilibrium state. Depending on the value of $mathcal{R}_0$, this state can be either endemic ($mathcal{R}_0> 1$), or infection-free ($mathcal{R}_0leq 1$). The global asymptotic stability of ...
متن کاملبررسی شیوع عفونت سل نهفته در کارکنان بیمارستان شهدای عشایر خرم آباد، 1394
Background : Despite of extensive global control programs of tuberculosis, the prevalence of this disease in underdeveloped and developing countries still remains high.Also the prevalence of latent TB infection in hospital staff has a particular importance. Materials and Methods: In a descriptive-analytic study conducted from March to June 2015 in Khorramabad Ashayer hospital on employees, afte...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
دوره 2014 شماره
صفحات -
تاریخ انتشار 2014